HPC tool

SIMUFLEX

Brownian dynamics of flexible bead-and-connector macromolecules.

About

SIMUFLEX is a suite of algorithms and tools for simulating the conformation and dynamics of flexible molecules and nanoparticles in dilute solution, using bead-and-connector models and Brownian dynamics.

Co-developed with the macromolecular dynamics group of Prof. García de la Torre at Universidad de Murcia.

Key features

Bead-and-connector dynamics

Coarse-grained model suitable for very large flexible macromolecules.

Solution properties calculation

Hydrodynamic and conformational properties from simulated trajectories.

Long-running collaboration

Mature tool with a base of published applications across biochemistry and materials.

Access

HPC tool

Download from UMU site

Free for academic use · co-developed with García de la Torre group (UMU)

http://leonardo.inf.um.es/macromol/programs/simuflex-4/simuflex-4.htm →

Cite this tool

SIMUFLEX: Algorithms and tools for simulation of the conformation and dynamics of flexible molecules and nanoparticles in dilute solution

García de la Torre J., Hernández Cifre J.G., Ortega A., Rodríguez Schmidt R., Fernandes M.X., Pérez Sánchez H.E., Pamies R. · Journal of Chemical Theory and Computation 5(10), 2606–2618, 2009

DOI: 10.1021/ct900284d