Achilles
Blind Docking Server
A priori blind docking — no binding site required.
About
Achilles is a web server for performing blind docking calculations: given a protein and a ligand, it explores potential binding sites across the whole protein surface without requiring prior knowledge of the binding pocket.
It is open to all users — no registration required — and a detailed prediction report is delivered by email.
Key features
Binding-site discovery
Finds candidate pockets for orphan or poorly-characterised targets.
Allosteric exploration
Identifies non-orthosteric pockets that may be functionally relevant.
Fast pre-screening
Useful as a first-pass filter before more expensive site-specific docking.
Access
Web server
Open the Achilles web server
Free web access · commercial licence available on request
https://bio-hpc.ucam.edu/aquiles/ →Cite this tool
Achilles: a Web Server for Blind Docking Calculations