HPC suite

BINDSURF

GPU-accelerated whole-protein-surface virtual screening.

About

BINDSURF docks each ligand of a library to the whole surface of a target protein, without assuming the location of the binding site. It returns information on potential binding sites and ligand poses ranked by scoring.

Built from scratch by the group on GPU architectures, BINDSURF can pre-screen large compound databases at speeds well beyond CPU-only methods, and its output can guide subsequent detailed virtual screening (MD, multiscale simulation).

Key features

Whole-protein-surface docking

No prior knowledge of the binding pocket required — useful for orphan targets.

GPU acceleration

All-atom docking on commodity GPUs, designed for throughput.

Pre-screening of large libraries

Fast first-pass for compound databases of millions of molecules.

Access

HPC suite

Request access by email

Academic use on request · commercial licence available

mailto:hperez@ucam.edu?subject=BINDSURF%20access →

Cite this tool

High-Throughput parallel blind Virtual Screening using BINDSURF

Sánchez-Linares I., Pérez-Sánchez H., Cecilia J.M., García J.M. · BMC Bioinformatics 13 (Suppl 14), S13, 2012

DOI: 10.1186/1471-2105-13-S14-S13