HPC suite

MetaScreener

HPC orchestrator for large-scale virtual screening campaigns.

About

MetaScreener is the BIO-HPC group flagship HPC orchestrator for virtual screening campaigns. It manages the full lifecycle of a campaign — input preparation, distribution across compute nodes, multi-program docking, consensus scoring and result aggregation — on libraries of up to 10⁷ compounds.

It has been used routinely in BIO-HPC drug-discovery programs, including blind-docking studies and the recently published ConFiLiS / dimethoxycurcumin work.

A formal methods paper describing MetaScreener is in preparation.

Key features

End-to-end campaign management

Inputs, scheduling, docking, scoring, reporting in one pipeline.

Scales to 10⁵–10⁷ compounds

Distributes large screens across HPC nodes and GPU pools.

Multi-engine consensus

Integrates outputs from several docking and scoring engines.

Access

HPC suite

Source code on GitHub

Open source · private SaaS deployment on demand · methods paper in preparation

https://github.com/bio-hpc →

Citation

Methods paper in preparation. In the meantime, please cite the GitHub repository or contact us directly.